Mathematik Informatik Technik
Campus Remagen
Joseph-Rovan-Allee 2
DE - 53424 Remagen
DE - 53424 Remagen
- Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard
Lin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter et al. - Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure
Oeing, Christian U.; Pepin, Mark E.; Saul, Kerstin B. et al. - Identification of NHLRC1 as a Novel AKT Activator from a Lung Cancer Epigenome-Wide Association Study (EWAS)
Faltus, Christian; Lahnsteiner, Angelika; Barrdahl, Myrto et al. - Pediatric T-ALL type-1 and type-2 relapses develop along distinct pathways of clonal evolution
Richter-Pechańska, Paulina; Kunz, Joachim B.; Rausch, Tobias et al. - Immunotyping of clinically divergent p.Phe508del homozygous monozygous cystic fibrosis twins
Schamschula, Esther; Hagmann, Wolfgang; Assenov, Yassen et al. - Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis
Goeppert, Benjamin; Stichel, Damian; Toth, Reka et al. - Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL
Wierzbinska, Justyna A.; Toth, Reka; Ishaque, Naveed et al. - Histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target
Orouji, Elias; Federico, Aniello; Larribère, Lionel et al. - Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma
Goeppert, Benjamin; Toth, Reka; Singer, Stephan et al. - Random forest-based modelling to detect biomarkers for prostate cancer progression
Toth, Reka; Schiffmann, Heiko; Hube-Magg, Claudia et al. - RnBeads 2.0: comprehensive analysis of DNA methylation data
Müller, Fabian; Scherer, Michael; Assenov, Yassen et al. - Enrichment analysis with EpiAnnotator
Pageaud, Yoann; Plass, Christoph; Assenov, Yassen - Intratumor heterogeneity in epigenetic patterns
Assenov, Yassen; Brocks, David; Gerhäuser, Clarissa - Maftools: efficient and comprehensive analysis of somatic variants in cancer
Mayakonda, Anand; Lin, De-Chen; Assenov, Yassen et al. - Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories
Gerhauser, Clarissa; Favero, Francesco; Risch, Thomas et al. - Circulating cytokines and small molecules follow distinct expression patterns in acute myeloid leukaemia
Islam, Mirazul; Mohamed, Elsa Haniffah; Esa, Ezalia et al. - Differential Analysis of Genetic, Epigenetic, and Cytogenetic Abnormalities in AML
Islam, Mirazul; Mohamed, Zahurin; Assenov, Yassen - DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
Brocks, David; Schmidt, Christopher R; Daskalakis, Michael et al. - Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability
Jäkel, Cornelia; Bergmann, Frank; Toth, Reka et al. - Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response
Bernhardt, Mathias; Novak, Daniel; Assenov, Yassen et al. - RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia
Lipka, Daniel B.; Witte, Tania; Toth, Reka et al. - Strategies for analyzing bisulfite sequencing data
Wreczycka, Katarzyna; Gosdschan, Alexander; Yusuf, Dilmurat et al. - DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
Oakes, Christopher C; Seifert, Marc; Assenov, Yassen et al. - Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis
Moran, Sebastian; Martínez-Cardús, Anna; Sayols, Sergi et al. - Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis
Weigel, Christoph; Veldwijk, Marlon R.; Oakes, Christopher C. et al. - Quantitative comparison of DNA methylation assays for biomarker development and clinical applications
Bock, Christoph; Halbritter, Florian; Carmona, Francisco J et al. - Mutational dynamics between primary and relapse neuroblastomas
Schramm, Alexander; Köster, Johannes; Assenov, Yassen et al. - Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation
Kunz, Joachim B.; Rausch, Tobias; Bandapalli, Obul R. et al. - Comprehensive analysis of DNA methylation data with RnBeads
Assenov, Yassen; Müller, Fabian; Lutsik, Pavlo et al. - Evolution of DNA Methylation Is Linked to Genetic Aberrations in Chronic Lymphocytic Leukemia
Oakes, Christopher C.; Claus, Rainer; Gu, Lei et al. - Identification and prioritization of genomic loci with disease-specific methylation
Assenov, Yassen - Intratumor DNA Methylation Heterogeneity Reflects Clonal Evolution in Aggressive Prostate Cancer
Brocks, David; Assenov, Yassen; Minner, Sarah et al. - A Prognostic DNA Methylation Signature for Stage I Non–Small-Cell Lung Cancer
Sandoval, Juan; Mendez-Gonzalez, Jesus; Nadal, Ernest et al. - Analyzing Epigenome Data in Context of Genome Evolution and Human Diseases
Feuerbach, Lars; Halachev, Konstantin; Assenov, Yassen et al. - Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues
Simmer, Femke; Brinkman, Arie B.; Assenov, Yassen et al. - Topological analysis and interactive visualization of biological networks and protein structures
Doncheva, Nadezhda T; Assenov, Yassen; Domingues, Francisco S et al. - A DNA methylation fingerprint of 1628 human samples
Fernandez, Agustin F.; Assenov, Yassen; Martin-Subero, Jose Ignacio et al. - A promoter DNA demethylation landscape of human hematopoietic differentiation
Calvanese, Vincenzo; Fernández, Agustín F.; Urdinguio, Rocío G. et al. - A Network-based Analysis of Polyanion-binding Proteins Utilizing Human Protein Arrays
Salamat-Miller, Nazila; Fang, Jianwen; Seidel, Christopher W. et al. - Computational analysis of human protein interaction networks
Ramírez, Fidel; Schlicker, Andreas; Assenov, Yassen et al. - Computing topological parameters of biological networks
Assenov, Yassen; Ramírez, Fidel; Schelhorn, Sven-Eric et al. - The implications of alternative splicing in the ENCODE protein complement
Tress, Michael L.; Martelli, Pier Luigi; Frankish, Adam et al. - A Network-based Analysis of Polyanion-binding Proteins Utilizing Yeast Protein Arrays
Salamat-Miller, Nazila; Fang, Jianwen; Seidel, Christopher W. et al.